Codons are the three base pair groups in mRNA (messenger RNA).
Anticodons are three bases in the tRNA (transfer RNA) that are complementary to the mRNA's codons. tRNA is actually connected to the amino acids which is coded for by the codon.
Although every codon codes for exactly one amino acid, a single tRNA can match more than one mRNA. That's because the 3rd position codon in the mRNA doesn't always have to match the tRNA's anticodon exactly. This is called the wobble position. If you look at codon sequences, the codons that code for one amino acid are always similar, except in the 3rd position. This helps eliminate the # of tRNAs needed in the cell – just another way evolution has tried to save energy.
Difference Between Codon And Anticodon
codons- grouping of three neucleotides that are the language of mRNA.
Anticodons- each tRNA has three bases that compliment the codon that it is associated with so that it can pair with the codon needed opposite its bases.
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An anticodon is a sequence of three adjacent nucleotides in transfer RNA that binds to a corresponding codon in messenger RNA and designates a specific amino acid during protein synthesis.